Extramedullary hematopoiesis masquerading as malignant neoplasm in a known case of plasmacytoma

To the Editor, Extramedullary hematopoiesis (EMH) is the presence of hemopoietic precursors outside the bone marrow. Usually, it is noted in patients with myeloproliferative disorder and congenital hematological diseases. The organs most commonly involved are the spleen, liver, and lymph nodes, but EMH has also been reported in a number of unusual sites such as, mediastinum and even breast. Although cases of myeloid metaplasia presenting as masses within various sites have been reported, to the best of our knowledge, no case of EMH masquerading as malignant neoplasm of neck in a case of plasma cell neoplasm has been documented. We hereby present such a case, where the diagnosis was made by fine-needle aspiration (FNA) cytology.